[RASMB] Empty voids

[Brian M. Baker]

Look up Brian Matthews.

-Brian

=========================================
Brian M. Baker
Associate Professor of Biochemistry
Director of Graduate Studies
Department of Chemistry and Biochemistry
251 Nieuwland Science Hall
University of Notre Dame
Notre Dame, Indiana 46556

Email: brian-baker at nd.edu
Office: 574 631 9810
Fax: 574 631 6652
Lab: 574 631 9775
Home page: www.nd.edu/~bakerlab



On Thu, Jun 3, 2010 at 12:08 PM, Dj Scott <Dj.Scott at nottingham.ac.uk> wrote:
> Hello all in RASMB-land.
>
> A question for you.
>
>
>
> If I make a void in a protein by mutating a larger residue to a smaller one
> in the hydrophobic core, what is the thermodynamic cost of this, and how
> would it be best to measure it.
>
>
>
> All thoughts welcome.
>
> Best
>
>
>
> Dave.
>
>>>>>>>>>>>>>>>>>>>>>>>>>>>
> Dr. David J. Scott
> Associate Professor in Physical Biochemistry
> National Centre for Macromolecular Hydrodynamics
> School of Biosciences
> University of Nottingham
> Sutton Bonington Campus
> Leicestershire. LE12 5RD.
> United Kingdom.
> Phone: +44 (0) 115 951 6221
> Fax: +44 (0) 115 951 6142
> Email: dj.scott at nottingham.ac.uk
> Web: www.nottingham.ac.uk/ncmh
>
>
>
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