[RASMB] SAUCE - x-ray optics for the AUC

[Matt Perugini]

Dear Olwyn,
 
My research group at the Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Australia would certainly be interested in supporting the SAUCE initiative. Our research program currently employs both AUC and SAXS to monitor enzyme oligomerization and shape, and could certainly see benefits from measuring both techniques simultaneously.
 
Best wishes,
 
Matt Perugini.

________________________________

From: rasmb-bounces at rasmb.bbri.org on behalf of Olwyn Byron
Sent: Fri 3/13/2009 10:40 AM
To: rasmb at rasmb-email.bbri.org
Subject: [RASMB] SAUCE - x-ray optics for the AUC



Dear RASMB Colleagues,

We have been invited to submit a full bid to the UK Science and
Technologies Facilities Council (STFC) to fund SAUCE - a hybrid
instrument in which an AUC (the Spin Analytical Centrifugal Fluid
Analyser (CFA)) is introduced into the I22 small angle x-ray
scattering (SAXS) beamline at the UK Diamond synchrotron.

SAUCE will offer the following advantages to the user:

1. Aggregates will be cleared from the sample in situ; scattering
data will be of a higher quality.

2. AUC modality will permit the separation or significant enrichment
of species in an interacting system; scattering curves (and thence
molecular envelopes) will be determined for the individual species.

3. It will be possible to acquire AUC and SAXS data simultaneously.

We are writing to you now to ask if you would be interested in using
SAUCE and would accordingly agree to being included in the list of
beneficiaries?

If so, please reply to this e-mail by return (and certainly before 24 March).

Many thanks and best wishes,

Olwyn Byron (University of Glasgow, UK)
Tom Laue (University of New Hampshire, US)
Nick Terrill (Diamond Synchrotron, UK)

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