[RASMB] SAUCE - x-ray optics for the AUC

[Mattia Rocco]

Dear Olwyn, Tom, and Nick,

I enthusiastically support your proposal, and I can clearly see 
applications to my own research, for instance to study the solution 
conformation of fibrin oligomers or fibrinogen-integrin complexes. Let me 
know if a more formal and detailed letter is needed, I will be glad to 
provide it.

With my best wishes,

Mattia
___________________________________________

Dr. Mattia Rocco
Biopolimeri e Proteomica
Istituto Nazionale per la Ricerca sul Cancro (IST)
c/o Centro per le Biotecnologie Avanzate (CBA)
IST c/o CBA, Largo Rosanna Benzi 10
I-16132 Genova, Italy

Phone: +39-0105737-310
Fax: +39-0105737-325
e-mail: mattia.rocco at istge.it



At 11:40 PM 3/12/2009 +0000, Olwyn Byron wrote:
>Dear RASMB Colleagues,
>
>We have been invited to submit a full bid to the UK Science and 
>Technologies Facilities Council (STFC) to fund SAUCE - a hybrid instrument 
>in which an AUC (the Spin Analytical Centrifugal Fluid Analyser (CFA)) is 
>introduced into the I22 small angle x-ray scattering (SAXS) beamline at 
>the UK Diamond synchrotron.
>
>SAUCE will offer the following advantages to the user:
>
>1. Aggregates will be cleared from the sample in situ; scattering data 
>will be of a higher quality.
>
>2. AUC modality will permit the separation or significant enrichment of 
>species in an interacting system; scattering curves (and thence molecular 
>envelopes) will be determined for the individual species.
>
>3. It will be possible to acquire AUC and SAXS data simultaneously.
>
>We are writing to you now to ask if you would be interested in using SAUCE 
>and would accordingly agree to being included in the list of beneficiaries?
>
>If so, please reply to this e-mail by return (and certainly before 24 March).
>
>Many thanks and best wishes,
>
>Olwyn Byron (University of Glasgow, UK)
>Tom Laue (University of New Hampshire, US)
>Nick Terrill (Diamond Synchrotron, UK)
>
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>RASMB at rasmb.bbri.org
>http://rasmb.bbri.org/mailman/listinfo/rasmb
>




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