[RASMB] Surface induced antibody aggregation?

David Hayes hayes at bbri.org
Wed Feb 2 14:21:00 PST 2005


RASMB members,

   John Philo stated in a 10-24-04 e-mail that "for one type of protein, I
see aggregation induced during the sedimentation velocity experiment, and
the extent of aggregate formation is characteristic of individual
centerpieces (the specific centerpiece, not just the type).  Thus this
represents some sort of surface-induced aggregation".  I would like to know
if any RASMB members have observed this behavior for antibodies,
particularly in charcoal filled epon centerpieces.

Thanks,  Allen Pekar  (Eli Lilly and Company)

(posted by David Hayes for Allen Pekar because of email setup concerns)





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