[RASMB] UltraScan workshop, June 1-4 2020

[Borries Demeler]

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Dear Colleagues,

We are happy to announce the 18th annual Analytical Ultracentrifugation
and UltraScan workshop scheduled for June 1-4, 2020 at the University
of Lethbridge in Southern Alberta.

**************************************************************************
        Solution Studies of Biological Macromolecules:

          From Experimental Design to Data Analysis
**************************************************************************

Additional information can be found online at:

	http://ultrascan.aucsolutions.com/workshop.php

The registration deadline is Friday, May 8, 2020.
A limited number of seats (15) are available on a first-come basis.

Course Contents:

The goal of this workshop is to provide participants with a solid
background in hydrodynamics, and to provide hands-on training with the
UltraScan-III software for high-resolution AUC experimental data analysis.
Topics include:

   * Hands-on Optima AUC Instrument Training, Cell Assembly, GMP automated Data Acquisition

   * Introduction to Hydrodynamics and Experimental Design

   * UltraScan hands-on software training:
      -- LIMS usage and data management
      -- Sedimentation Velocity Analysis with 2DSA, Monte Carlo, dC/dt
      -- PCSA, Genetic Algorithms, Multi-wavelength analysis, van Holde - Weischet analysis

   * Applications:
      -- protein-nucleic acid interactions
      -- viral vector loading
      -- protein-protein interactions
      -- composition, anisotropy and diffusion measurements
      -- purity measurements, aggregation quantification
      -- GMP processing of sedimentation velocity data
      -- Multi-wavelength measurements and spectral analysis
      -- Result Interpretation and Reporting
      -- reversible oligomerization, hetero-association

Participants will learn how to optimally design AUC experiments to solve
problems in a wide range of domains applicable for hydrodynamic study, and
gain proficiency with the UltraScan-III software and the high-performance
computing backend, as well as the LIMS database system. Participants are
encouraged to bring their own data to be analyzed with expert assistance
during the workshop. Participants will learn how to use high-performance
computing through the LIMS Science Gateway to analyze sedimentation
velocity data using various modeling approaches based on whole boundary
finite element solutions, and to interpret the results.

We look forward to seeing you in Lethbridge! 

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Borries Demeler, PhD, Professor
Canada 150 Research Chair in Biophysics          
Department of Chemistry and Biochemistry     
University of Lethbridge, Alberta    and   University of Montana            
e-mail: demeler at uleth.ca                   Missoula Montana, 59812          
Phone: (406) 285-1935                      borries.demeler at umontana.edu