[RASMB] Available post doctoral position at Genentech

[Steve Shire]

A postdoctoral position is available in the Late Stage Pharmaceutical  
and Process Development Department in the lab of Steven J. Shire to  
investigate the rheological properties of monoclonal antibodies.  
Previous work done in this research program has established a link  
between protein self-association behavior and the viscosity of the Mab  
formulation. In particular studies using three closely related MAbs  
have focused on contributions due to sequence differences, which has  
resulted in collaboration with Mab Engineering in Research. Several  
charge based mutants have been generated and will be used to further  
explore the linkage between charge distribution and viscoelastic  
behavior.

Requirements:

A Ph.D. in biophysics, biophysical chemistry or a related discipline.   
The candidate must have excellent biophysical and/or protein  
biochemistry skills and hands-on experience or knowledge of the use of  
different biophysical analytical technologies. The candidate must be  
highly self-motivated, have excellent organization, communication,  
interpersonal and collaborative skills, and be willing to work  
independently.

To apply: Please contact and submit resume to Steve Shire at shire.steve at gene.com


Steven J. Shire, Ph.D.
Staff Scientist and Group Leader
Late Stage Pharmaceutical and Processing Development Dept.
MS #56-1A
Genentech, Inc.
1 DNA Way
S. San Francisco, CA 94080
650-225-2077 (VOICE)
shire.steve at gene.com

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