[RASMB] Hb tetramer

[mitrana at mail.utexas.edu]

Hello All
Two questions, related ones -

1. Is a S20,w value of 5.01 too high for a DEOXY Hb tetramer of 67180  
Da MW? This gives a f/f0 of around 1.08. Just a reminder that deoxy Hb  
tetramer does not dissociate to a dimer much (dissociation constant ~  
10^-11 M).

2. can such an anomaly occur due to Hb interactions with the  
components of the buffer - in this case 2 mM of Inositol  
hexakisphosphate (IHP)?

Glad to hear any comments and/or references to papers.

Mitra