[RASMB] release of DCDT+ version 2

John Philo jphilo at mailway.com
Mon Feb 27 07:56:56 PST 2006


A major update (virtually an entire re-write) to DCDT+ is now available.
Version 2.0.2 can be downloaded from
http://www.jphilo.mailway.com/download.htm

This version is designed to be even easier to use, especially for beginners.
It has an entirely new user interface:
   * multiple analysis documents can be open at the same time
   * overlay graphs of the g(s*) curves from different samples are
     generated automatically, allowing easy comparisons (for 
     example dilution series to look for reversible association)
   * an Explorer-style navigation tree allows movement among 
     different analysis steps and between different analyses
   * "standard mode" hides advanced options; "advanced mode"
     shows all the bells and whistles
   * the usual Windows features you expect: a tool bar; analysis 
     documents appear in "My Recent Documents" just like your
     other documents; right-click context menus

Another major new feature is a new fitting algorithm that totally eliminates
the systematic errors in hydrodynamic properties arising from using too long
a time span (too many scans). This new algorithm gives S, D, and M values
accurate to 0.1% (as good or better than direct boundary fitting methods),
while retaining the ease of use and algebraic removal of systematic noise
advantages of the DCDT approach. 

In this version you can simply load the entire run in one operation, then
'tune' through the run using slider controls to select the scans you want to
analyze, seeing the results as you go. An 'auto adjust' wizard will even
select those scans for you. Other program wizards automate tasks such as
meniscus location, jitter removal, and fringe jump removal.

Some other enhancements:
   * g(s*) distributions can be optionally normalized (total area set to 
     100%); this is great for comparing data at different 
     concentrations or from different optical systems
   * reads fluorescence scans and absorbance intensity files
     (including pseudo-absorbance for two samples per cell)
   * during fitting a graph shows the progress of the fit
     (overlaid data and fitted function, plus residual plot)
   * new graphics package has right-click context menus for 
     customization, printing, and exporting as JPG, PNG, or 
     BMP formats in addition to metafiles (scalable vector)
   * an even better context-sensitive Help file (F1 key brings up
     Help for the page you are working on with more extensive tutorials; 
     this is now also available re-formatted as a manual for those who 
     wish to print one

Note that installation of version 2, and its 60-day free trial period, is
independent of version 1.xx (the old version is not removed, and the new
goes into a new folder by default).

John




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