[RASMB] Origin software and vbar

[John Philo]

Yes, this is a major bug that I believe is present in the current release.
Exactly when this bug was introduced I'm not sure (it was not present in
some earlier versions). We discovered it during one of the classes in Palo
Alto, ~6 months ago if I remember correctly. I don't know the status of a
fix, you'll have to ask Beckman about that.

John Philo

-----Original Message-----
From: rasmb-admin at server1.bbri.org [mailto:rasmb-admin at server1.bbri.org] On
Behalf Of John McGeehan
Sent: Wednesday, May 04, 2005 3:57 AM
To: rasmb at server1.bbri.org
Subject: [RASMB] Origin software and vbar


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Dear AUC users,

Has anyone encountered this software problem before:

When using the Beckman Origin Self-Association Model changing the 
partial specific volume entered into the fit options does not affect the 
results.  Even when changed by a factor of 100, the calculated 
molecular weight after fitting remains constant to 3 decimal places. 

Any help appreciated.

Regards,
John.
 
-- 
Dr John McGeehan
Senior Research Fellow
Biophysics Laboratories
University of Portsmouth

john.mcgeehan at port.ac.uk
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