[Rasmb] postdoctoral position, Grenoble France.

Christine Ebel christine.ebel at ibs.fr
Thu Sep 15 14:32:01 PDT 2005


Dear Collegues,
I have a postdoctoral position available. 
See below and the attached file
Please inform who will be interested.
Christine EBEL


Two-year postdoctoral position at IBS Grenoble (France) 
CEA-funded

CHARACTERISATION AND STABILIZATION OF SOLUBILISED MEMBRANE PROTEINS

      Determination and control of the association states of membrane
proteins is one of the challenges of modern biophysics. The effects of
detergent on membrane proteins stability, auto-association and
crystallisation capability are not well understood. 
      The project is to adapt new methods, mainly analytical
ultracentrifugation, for the characterization of different membrane
proteins, including Ca++ ATPase and transporters. Detergent-solubilised
membrane proteins but also complexes with synthetic lipid derivatives
(nanosomes) will be studied. The possible relationships between solvent
composition and membrane proteins solubility/auto-association will be
investigated. 
      The project will be carried out in collaboration with G. Brandolin,
J.-M. Jault and E. Pebay-Peyroula (Grenoble France), M. le Maire and C.
Mioskowski, (Saclay France), and P. Schuck (NIH, USA). 
           
Techniques to be used: analytical ultracentrifugation, small angle neutron
scattering, liquid chromatography, thermodynamic approaches, molecular
biology and biochemical techniques.

Formal conditions (exceptions are possible in cases of outstanding
qualifications and non-French curricula): candidates should hold a PhD and
not be older than 29 years; the contract is initially for 1 year, renewable
for 1 more year, and will start in 2006. 
Candidates should send a cover letter describing their expertise and
interest for the position, a detailed CV, list of publications, and at least
two letters of recommendation or names of referees.

Send applications to:	 Christine EBEL (christine.ebel at ibs.fr)
Laboratoire de Biophysique Moléculaire, Institut de Biologie Structurale 
UMR 5075 : CEA - CNRS - UJF
41 rue Jules Horowitz, 38027 Grenoble Cedex 01, France
Tel: (33) (0)4 38 78 96 38   Fax:   (33) (0)4 38 78 54 94	
http://www.ibs.fr/content/ibs_eng/presentation/lab/lbm/ebel.htm

Christine EBEL
Institut de Biologie Structurale UMR 5075 CEA-CNRS-UJF
41 rue Jules Horowitz, 38027 Grenoble Cedex 1, France
Tel (33) (0) 4 38 78 96 38; Fax (33) (0) 4 38 78 54 94 christine.ebel at ibs.fr


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