[RASMB] on low s value peak in sedfit

[Qin Zou]

Dear experts,
I have been reading some discussions on low s value peaks using sedfit in 
this group. I have such a partial peak with smin at 0.1s. I have tried Dr. 
Schuck's method that is to increase s-min value gradually while monitoring 
the rmsd. Here is some of the results:
s-min: 0.2s     0.5s    1.0s            1.2s            1.4s 
rmsd:  0.005249 0.0053  0.005556        0.005580        0.005588

The height of the partial peak did drop but never completely disappears. 
Couple of questions:
1)Is the increase of the rmsd shown above considered significant?
2)If there is a sedimenting component at this low s, how do I integrate 
this partial peak and the other complete peaks? It seems that moving 
around s-min affects the integration alot. 
3)There is also a little partial peak at s-max. If I only want to know the 
loading percentage of all the aggregates, should I just integrate all the 
way to the s-max?

Thanks in advance.
Regards,

Chin  Zou
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