<br><font size=2 face="sans-serif">Dear experts,</font>
<br><font size=2 face="sans-serif">I have been reading some discussions on low s value peaks using sedfit in this group. I have such a partial peak with smin at 0.1s. I have tried Dr. Schuck's method that is to increase s-min value gradually while monitoring the rmsd. Here is some of the results:</font>
<br><font size=2 face="sans-serif">s-min: 0.2s 0.5s 1.0s 1.2s 1.4s </font>
<br><font size=2 face="sans-serif">rmsd: 0.005249 0.0053 0.005556 0.005580 0.005588</font>
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<br><font size=2 face="sans-serif">The height of the partial peak did drop but never completely disappears. Couple of questions:</font>
<br><font size=2 face="sans-serif">1)Is the increase of the rmsd shown above considered significant?</font>
<br><font size=2 face="sans-serif">2)If there is a sedimenting component at this low s, how do I integrate this partial peak and the other complete peaks? It seems that moving around s-min affects the integration alot. </font>
<br><font size=2 face="sans-serif">3)There is also a little partial peak at s-max. If I only want to know the loading percentage of all the aggregates, should I just integrate all the way to the s-max?</font>
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<br><font size=2 face="sans-serif">Thanks in advance.</font>
<br><font size=2 face="sans-serif">Regards,</font>
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<br><font size=2 face="sans-serif">Chin Zou</font>