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</o:shapelayout></xml><![endif]--></head><body lang=EN-US link=blue vlink=purple><div class=WordSection1><p class=MsoNormal style='margin-left:.5in'><o:p> </o:p></p><p class=MsoNormal style='margin-left:.5in'><o:p> </o:p></p><div align=center><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;border-collapse:collapse'><tr><td width="100%" valign=top style='width:100.0%;padding:0in 0in 0in 0in'><div align=center><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;border-collapse:collapse'><tr><td valign=top style='background:#F7F7F7;padding:33.75pt 0in 33.75pt 0in'><div align=center><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width=600 style='width:6.25in;border-collapse:collapse'><tr><td width=600 valign=top style='width:6.25in;padding:0in 0in 0in 0in'><div align=center><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 style='max-width:6.25in;border-collapse:collapse'><tr><td valign=top style='padding:0in 0in 0in 0in'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;border-collapse:collapse'><tr><td valign=top style='padding:6.75pt 6.75pt 6.75pt 6.75pt'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 align=left width="100%" style='width:100.0%;border-collapse:collapse'><tr><td valign=top style='padding:0in 6.75pt 0in 6.75pt'><p class=MsoNormal align=center style='text-align:center'><img width=564 height=540 style='width:5.875in;height:5.625in' id="_x0000_i1025" src="https://gallery.mailchimp.com/6dbb03108468b01ea4f9d2ad2/images/84093648-968d-419e-a392-4b41d1ced9dc.jpg" alt="https://gallery.mailchimp.com/6dbb03108468b01ea4f9d2ad2/images/84093648-968d-419e-a392-4b41d1ced9dc.jpg"><o:p></o:p></p></td></tr></table></td></tr></table><p class=MsoNormal><o:p> </o:p></p><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;border-collapse:collapse;min-width: 100%;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><tr><td valign=top style='padding:6.75pt 0in 0in 0in;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 align=left width="100%" style='width:100.0%;border-collapse:collapse;margin-left:-2.25pt;margin-right:-2.25pt;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><tr><td width=600 valign=top style='width:6.25in;padding:0in 0in 0in 0in;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 align=left width="100%" style='width:100.0%;border-collapse:collapse;max-width:100%;min-width: 100%;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><tr><td valign=top style='padding:0in 13.5pt 6.75pt 13.5pt;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;word-break:break-word'><h1><strong><span style='font-family:"Helvetica",sans-serif'>“</span></strong><em><span style='font-family:"Helvetica",sans-serif'>Applications of Small Angle Scattering to Structural Biology: An Introduction.</span></em><strong><span style='font-family:"Helvetica",sans-serif'>” </span></strong><o:p></o:p></h1></td></tr></table></td></tr></table></td></tr></table><p class=MsoNormal><span style='font-size:10.0pt;font-family:"Times New Roman",serif'><o:p></o:p></span></p></td></tr></table></div></td></tr></table></div></td></tr><tr><td valign=top style='background:white;padding:27.0pt 0in 33.75pt 0in;background:cover;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;background-size: cover;background-position-x:50%;background-position-y:50%' id=templateBody><div align=center><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width=600 style='width:6.25in;border-collapse:collapse;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><tr><td width=600 valign=top style='width:6.25in;padding:0in 0in 0in 0in;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><div align=center><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 style='max-width:6.25in;border-collapse:collapse;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><tr><td valign=top style='padding:0in 0in 0in 0in;background:cover;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;background-size: cover;background-position-x:50%;background-position-y:50%'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;border-collapse:collapse;min-width: 100%;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><tr><td valign=top style='padding:6.75pt 0in 0in 0in;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 align=left width="100%" style='width:100.0%;border-collapse:collapse;margin-left:-2.25pt;margin-right:-2.25pt;max-width:100%;min-width: 100%;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><tr><td width=600 valign=top style='width:6.25in;padding:0in 0in 0in 0in;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;word-break:break-word'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 align=left width="100%" style='width:100.0%;border-collapse:collapse'><tr><td valign=top style='padding:0in 13.5pt 6.75pt 13.5pt'><h3><strong><span style='font-family:"Helvetica",sans-serif'>On behalf of the organizing committee, we are pleased to announce a workshop on “</span></strong><em><span style='font-family:"Helvetica",sans-serif'>Applications of Small Angle Scattering to Structural Biology: An Introduction.</span></em><strong><span style='font-family:"Helvetica",sans-serif'>” </span></strong><o:p></o:p></h3><p class=MsoNormal style='mso-margin-top-alt:7.5pt;margin-right:0in;margin-bottom:7.5pt;margin-left:0in;line-height:150%;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><strong><span style='font-size:12.0pt;line-height:150%;font-family:"Helvetica",sans-serif;color:gray'>This workshop will take place on Friday, July 20<sup>th</sup>, 2018 at this year’s American Crystallographic Association (ACA) Meeting in Toronto, Canada. The meeting itself will run from July 20-24.</span></strong><span style='font-size:12.0pt;line-height:150%;font-family:"Helvetica",sans-serif;color:gray'><br> <br>Over the past two decades, SAS has become a mainstay technique for the study of structure and composition in solution for structural biologists around the world. In contrast to the more intensive SAS courses in Europe that extend across several days, this single-day workshop will be comprised of carefully constructed lectures and tutorials to serve as an introduction to investigators new to the technique. The workshop format will include lectures and a selection of hands-on practical exercises. Throughout the workshop the emphasis will be on practical application: knowing how to judge data quality, how to troubleshoot during data collection, and the expectations for a successful experiment and acceptable publication. Students will also learn about aspects of home laboratory data collection and will be introduced to experiments at national user facilities (synchrotrons and research reactors). <br> <br>Students will be expected to bring laptops with the appropriate pre-installed software. Extra laptops will be provided in case of unexpected hardware or software issues on-site, and network connectivity will be provided as part of the course, as some exercises and tutorials will reply on external computer-server resources.Preloaded portable disks and memory sticks will be provided to help reduce the need for large downloads over conference bandwidth.<br> <br><em><b><span style='font-family:"Helvetica",sans-serif'>We thank Anton-Paar, Rigaku Corporation, SAXSLAB, and Wyatt Technology Corporation for their kind support of this event.</span></b></em><br> <br><strong><span style='font-family:"Helvetica",sans-serif'>Tentative Program Schedule</span></strong><br> <o:p></o:p></span></p><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width=670 style='width:502.5pt;border-collapse:collapse;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><tr><td width=126 style='width:94.5pt;padding:0in 0in 0in 0in;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><p class=MsoNormal><strong><span style='font-family:"Calibri",sans-serif'>Time</span></strong><o:p></o:p></p></td><td width=545 style='width:408.75pt;padding:0in 0in 0in 0in;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><p class=MsoNormal><strong><span style='font-family:"Calibri",sans-serif'>Topic</span></strong><o:p></o:p></p></td></tr><tr><td width=126 style='width:94.5pt;padding:0in 0in 0in 0in;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><p class=MsoNormal>8:00 AM<o:p></o:p></p></td><td width=545 style='width:408.75pt;padding:0in 0in 0in 0in;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><p class=MsoNormal><strong><span style='font-family:"Calibri",sans-serif'>Registration and Software Installation Help; Speaker Introduction</span></strong><o:p></o:p></p></td></tr><tr><td width=126 style='width:94.5pt;padding:0in 0in 0in 0in;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><p class=MsoNormal>8:30 AM<o:p></o:p></p></td><td width=545 style='width:408.75pt;padding:0in 0in 0in 0in;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><p class=MsoNormal><strong><span style='font-family:"Calibri",sans-serif'>BioSAS: Overview </span></strong><br><em><span style='font-family:"Calibri",sans-serif'>Why is SAS helpful?</span></em><o:p></o:p></p></td></tr><tr><td width=126 style='width:94.5pt;padding:0in 0in 0in 0in;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><p class=MsoNormal>9:00 AM<o:p></o:p></p></td><td width=545 style='width:408.75pt;padding:0in 0in 0in 0in;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><p class=MsoNormal><strong><span style='font-family:"Calibri",sans-serif'>The Scattering Profile </span></strong><br><em><span style='font-family:"Calibri",sans-serif'>Guinier analysis, concentration, monodispersity, etc.</span></em><o:p></o:p></p></td></tr><tr><td width=126 style='width:94.5pt;padding:0in 0in 0in 0in;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><p class=MsoNormal>9:30 AM<o:p></o:p></p></td><td width=545 style='width:408.75pt;padding:0in 0in 0in 0in;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><p class=MsoNormal><strong><span style='font-family:"Calibri",sans-serif'>Tutorial 1: Basic Data Analysis I with RAW </span></strong><br><em><span style='font-family:"Calibri",sans-serif'>Is this good data? Radiation Damage?</span></em><o:p></o:p></p></td></tr><tr><td width=126 style='width:94.5pt;padding:0in 0in 0in 0in;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><p class=MsoNormal>10:00 AM<o:p></o:p></p></td><td width=545 style='width:408.75pt;padding:0in 0in 0in 0in;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><p class=MsoNormal><em><span style='font-family:"Calibri",sans-serif'>Coffee Break</span></em><o:p></o:p></p></td></tr><tr><td width=126 style='width:94.5pt;padding:0in 0in 0in 0in;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><p class=MsoNormal>10:15 AM<o:p></o:p></p></td><td width=545 style='width:408.75pt;padding:0in 0in 0in 0in;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><p class=MsoNormal><strong><span style='font-family:"Calibri",sans-serif'>Data Analysis: Model-independent Features </span></strong><br><em><span style='font-family:"Calibri",sans-serif'>Molecular Weight Determination, Invariant Plots and Flexibility, The P(r) function</span></em><o:p></o:p></p></td></tr><tr><td width=126 style='width:94.5pt;padding:0in 0in 0in 0in;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><p class=MsoNormal>11:00 AM<o:p></o:p></p></td><td width=545 style='width:408.75pt;padding:0in 0in 0in 0in;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><p class=MsoNormal><strong><span style='font-family:"Calibri",sans-serif'>Tutorial 2: Basic Data Analysis II with RAW </span></strong><br><em><span style='font-family:"Calibri",sans-serif'>Calculate a P(r) function, determine Molecular Weight, D<sub>max</sub>, R<sub>g</sub>, Volume, etc.</span></em><o:p></o:p></p></td></tr><tr><td width=126 style='width:94.5pt;padding:0in 0in 0in 0in;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><p class=MsoNormal>12:00 PM<o:p></o:p></p></td><td width=545 style='width:408.75pt;padding:0in 0in 0in 0in;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><p class=MsoNormal><strong><span style='font-family:"Calibri",sans-serif'>Working Lunch</span></strong> - <strong><span style='font-family:"Calibri",sans-serif'>Laboratory Source SAXS </span></strong><br><em><span style='font-family:"Calibri",sans-serif'>Discussion with Scientists, Experimental Advice</span></em><o:p></o:p></p></td></tr><tr><td width=126 style='width:94.5pt;padding:0in 0in 0in 0in;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><p class=MsoNormal>1:00 PM<o:p></o:p></p></td><td width=545 style='width:408.75pt;padding:0in 0in 0in 0in;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><p class=MsoNormal><strong><span style='font-family:"Calibri",sans-serif'>SEC-SAXS </span></strong><br><em><span style='font-family:"Calibri",sans-serif'>Application and Practical Considerations</span></em><o:p></o:p></p></td></tr><tr><td width=126 style='width:94.5pt;padding:0in 0in 0in 0in;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><p class=MsoNormal>1:30 PM<o:p></o:p></p></td><td width=545 style='width:408.75pt;padding:0in 0in 0in 0in;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><p class=MsoNormal><strong><span style='font-family:"Calibri",sans-serif'>Sample Preparation</span></strong><br><em><span style='font-family:"Calibri",sans-serif'>Sample purification and preparation, aggregation, buffer selection, etc</span></em><o:p></o:p></p></td></tr><tr><td width=126 style='width:94.5pt;padding:0in 0in 0in 0in;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><p class=MsoNormal>1:45 PM<o:p></o:p></p></td><td width=545 style='width:408.75pt;padding:0in 0in 0in 0in;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><p class=MsoNormal><strong><span style='font-family:"Calibri",sans-serif'>Complementary Biophysical Methods for Sample Assessment </span></strong><br><em><span style='font-family:"Calibri",sans-serif'>The importance of supporting biophysical methods including static and dynamic light scattering and analytical ultracentrifugation </span></em><o:p></o:p></p></td></tr><tr><td width=126 style='width:94.5pt;padding:0in 0in 0in 0in;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><p class=MsoNormal>2:00 PM<o:p></o:p></p></td><td width=545 style='width:408.75pt;padding:0in 0in 0in 0in;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><p class=MsoNormal><strong><span style='font-family:"Calibri",sans-serif'>Data Analysis: Model-dependent Analysis of SAS Data</span></strong><br><em><span style='font-family:"Calibri",sans-serif'>Calculated scattering profiles from atomic models, Shape reconstruction, Atomistic modeling</span></em><o:p></o:p></p></td></tr><tr><td width=126 style='width:94.5pt;padding:0in 0in 0in 0in;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><p class=MsoNormal>2:30 PM<o:p></o:p></p></td><td width=545 style='width:408.75pt;padding:0in 0in 0in 0in;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><p class=MsoNormal><strong><span style='font-family:"Calibri",sans-serif'>Tutorial 3: </span></strong><em><b><span style='font-family:"Calibri",sans-serif'>Three-dimensional modeling from SAS data</span></b></em><o:p></o:p></p></td></tr><tr><td width=126 style='width:94.5pt;padding:0in 0in 0in 0in;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><p class=MsoNormal>3:15 PM<o:p></o:p></p></td><td width=545 style='width:408.75pt;padding:0in 0in 0in 0in;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><p class=MsoNormal><em><span style='font-family:"Calibri",sans-serif'>Coffee Break</span></em><o:p></o:p></p></td></tr><tr><td width=126 style='width:94.5pt;padding:0in 0in 0in 0in;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><p class=MsoNormal>3:30 PM<o:p></o:p></p></td><td width=545 style='width:408.75pt;padding:0in 0in 0in 0in;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><p class=MsoNormal><em><b><span style='font-family:"Calibri",sans-serif'>Guest Research Lecture</span></b></em><strong><span style='font-family:"Calibri",sans-serif'> – Thomas Grant, Research Asst. Professor, University of Buffalo/Hauptman-Woodward Medical Research Institute</span></strong><o:p></o:p></p></td></tr><tr><td width=126 style='width:94.5pt;padding:0in 0in 0in 0in;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><p class=MsoNormal>4:30 PM<o:p></o:p></p></td><td width=545 style='width:408.75pt;padding:0in 0in 0in 0in;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><p class=MsoNormal><strong><span style='font-family:"Calibri",sans-serif'>SANS and Contrast Variation </span></strong><o:p></o:p></p></td></tr><tr><td width=126 style='width:94.5pt;padding:0in 0in 0in 0in;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><p class=MsoNormal>5:00 PM<o:p></o:p></p></td><td width=545 style='width:408.75pt;padding:0in 0in 0in 0in;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><p class=MsoNormal><strong><span style='font-family:"Calibri",sans-serif'>Publishing SAS data </span></strong><o:p></o:p></p></td></tr><tr><td width=126 style='width:94.5pt;padding:0in 0in 0in 0in;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><p class=MsoNormal>5:30 PM<o:p></o:p></p></td><td width=545 style='width:408.75pt;padding:0in 0in 0in 0in;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><p class=MsoNormal><strong><span style='font-family:"Calibri",sans-serif'>Conclusion</span></strong><o:p></o:p></p></td></tr></table><p class=MsoNormal style='line-height:150%'><span style='font-size:12.0pt;line-height:150%;font-family:"Helvetica",sans-serif;color:gray'> <br><em><span style='font-family:"Helvetica",sans-serif'>Pre-registration is mandatory. The fee to attend is</span></em>: <o:p></o:p></span></p><ul type=disc><li class=MsoNormal style='color:gray;mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;line-height:150%;mso-list:l0 level1 lfo3;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><span style='font-size:12.0pt;line-height:150%;font-family:"Helvetica",sans-serif'>Student (undergrad, grad or postdoctoral) - $185 (CAN)<o:p></o:p></span></li><li class=MsoNormal style='color:gray;mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;line-height:150%;mso-list:l0 level1 lfo3;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><span style='font-size:12.0pt;line-height:150%;font-family:"Helvetica",sans-serif'>Corporate - $355 (CAN)<o:p></o:p></span></li><li class=MsoNormal style='color:gray;mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;line-height:150%;mso-list:l0 level1 lfo3;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><span style='font-size:12.0pt;line-height:150%;font-family:"Helvetica",sans-serif'>Non-corporate or non-student - $185 (CAN)<o:p></o:p></span></li></ul><p class=MsoNormal style='line-height:150%'><span style='font-size:12.0pt;line-height:150%;font-family:"Helvetica",sans-serif;color:gray'>Lunch will be included.<br> <br><em><b><span style='font-family:"Helvetica",sans-serif'>Contact: </span></b></em><br><strong><span style='font-family:"Helvetica",sans-serif'>Kushol Gupta, Perelman School of Medicine, University of Pennsylvania. </span></strong></span><a href="mailto:kgupta@upenn.edu"><span style='font-size:12.0pt;line-height:150%;font-family:"Helvetica",sans-serif;color:#00ADD8'>kgupta@upenn.edu</span></a><span style='font-size:12.0pt;line-height:150%;font-family:"Helvetica",sans-serif;color:gray'><br> <br><em><span style='font-family:"Helvetica",sans-serif'>Confirmed Instructors:</span></em><br> <br>Angela Criswell, Rigaku Corporation<br>Srinivas Chakravarthy, BioCAT Group, Advanced Photon Source<br>Richard Gillilan, Macromolecular Diffraction Facility, Cornell High Energy Synchrotron Source<br>Thomas Grant, University of Buffalo/Hauptman-Woodward Medical Research Institute<br>Jesse Hopkins, BioCAT Group, Advanced Photon Source<br>Maxim Petoukhov, BIOSAXS Group, EMBL Hamburg<br>Soren Skou, XENOCS (SAXSLAB)<br> <br>More information is available at:<br></span><a href="https://upenn.us16.list-manage.com/track/click?u=6dbb03108468b01ea4f9d2ad2&id=c23962f609&e=6031dddf6d"><span style='font-size:12.0pt;line-height:150%;font-family:"Helvetica",sans-serif;color:#00ADD8'>http://www.amercrystalassn.org/2018-workshops</span></a><span style='font-size:12.0pt;line-height:150%;font-family:"Helvetica",sans-serif;color:gray'> <br></span><a href="https://upenn.us16.list-manage.com/track/click?u=6dbb03108468b01ea4f9d2ad2&id=a6594b9e23&e=6031dddf6d"><span style='font-size:12.0pt;line-height:150%;font-family:"Helvetica",sans-serif;color:#00ADD8'>http://www.amercrystalassn.org/2018-meeting-homepage</span></a><span style='font-size:12.0pt;line-height:150%;font-family:"Helvetica",sans-serif;color:gray'> <o:p></o:p></span></p><div><div><div id="_com_1"><p class=MsoNormal style='line-height:150%'><span style='font-size:12.0pt;line-height:150%;font-family:"Helvetica",sans-serif;color:gray'> <o:p></o:p></span></p></div></div></div></td></tr></table></td></tr></table></td></tr></table><p class=MsoNormal><o:p> </o:p></p><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;border-collapse:collapse;min-width: 100%;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><tr><td style='padding:13.5pt 13.5pt 13.5pt 13.5pt;min-width: 100%;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;border-collapse:collapse;min-width: 100%;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><tr><td style='padding:0in 0in 0in 0in;min-width: 100%;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'></td></tr></table></td></tr></table><p class=MsoNormal><span style='font-size:10.0pt;font-family:"Times New Roman",serif'><o:p></o:p></span></p></td></tr></table></div></td></tr></table></div></td></tr><tr><td valign=top style='background:#333333;padding:33.75pt 0in 47.25pt 0in;background:cover;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;background-size: cover;background-position-x:50%;background-position-y:50%' id=templateFooter><div align=center><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width=600 style='width:6.25in;border-collapse:collapse;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><tr><td width=600 valign=top style='width:6.25in;padding:0in 0in 0in 0in;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><p class=MsoNormal align=center style='text-align:center'><o:p> </o:p></p></td></tr></table></div></td></tr></table></div></td></tr></table></div><p class=MsoNormal style='margin-bottom:12.0pt'><o:p> </o:p></p></div></body></html>