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</o:shapelayout></xml><![endif]--></head><body lang=EN-US link=blue vlink=purple><div class=WordSection1><p class=MsoNormal><b><span style='font-size:11.0pt;font-family:"Calibri","sans-serif"'>ACA Training Workshop WK.01<o:p></o:p></span></b></p><p class=MsoNormal><b><span style='font-size:11.0pt;font-family:"Calibri","sans-serif"'>Biological Small Angle Solution Scattering Theory and Practice<o:p></o:p></span></b></p><p class=MsoNormal><b><span style='font-size:11.0pt;font-family:"Calibri","sans-serif"'>2013 ACA meeting in Hawaii<o:p></o:p></span></b></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif"'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif"'>Reserve your space now! The early registration discount ends May 31*.<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif"'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif"'>Small angle solution scattering (SAS) has recently experienced a dramatic increase in popularity within the structural biology community.<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif"'>As molecular biological systems of interest become ever increasingly complex, SAS is providing valuable insight into structure and conformational behavior in solution. The availability of synchrotron radiation and neutron sources, commercial lab-source SAXS instrumentation, low-noise detectors, powerful computing hardware, and better algorithms has made the technique accessible to a much larger audience than ever before.<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif"'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif"'>This dual-track workshop brings together leading beamline scientists as well as experts in laboratory-based BioSAXS sources to provide a unique, practical “HOW TO” course in SAS data collection, processing, and interpretation.<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif"'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif"'>Track A: Getting Started in Biological Small Angle Solution Scattering: your practical HOW TO guide.<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif"'> Topics: Basics of scattering, Guinier analysis, monodispersity & aggregation, Kratky plots,<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif"'> folding & flexibility, molecular mass determination, P(r) function, sample preparation and <o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif"'> characterization tips, shape reconstruction, using lab sources, neutron scattering basics, <o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif"'> publishing your first data: what you should know.<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif"'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif"'> Speakers: Angela Chriswell (Rigaku), Javier Perez (Soleil), Srinivas Chakravarthy (APS), <o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif"'> Jill Trewhella (U. Sydney), Richard Gillilan (MacCHESS, Cornell U.), Andreas Keilbach (Anton Paar), <o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif"'> Juergen Graf (Incoatec), (Bruker speaker, to be confirmed)<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif"'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif"'>Track B: Using Advanced Methods in Biological Small Angle Solution Scattering<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif"'> Topics: evaluating SAXS data, molecular mass, flexibility, modeling software: FOXS, MES, <o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif"'> FoxDOCK, AllosMod-FOXS, strategy, inference-free data, similarity maps, contrast matched <o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif"'> heavy atom labeling, ensemble analysis, NMR+SAXS, ab initio modeling at the residue level,<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif"'> building a lab source for BioSAXS.<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif"'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif"'> Speakers: Robert Rambo, Michal Hammel, Greg Hura (ALS), Kushol Gupta (Perelman School of Medicine, U. Penn)<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif"'> Andreas Keilbach (Anton Paar), Juergen Graf (Incoatec), (Bruker speaker, to be confirmed), <o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif"'> Angela Chriswell (Rigaku), and others to be confirmed.<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif"'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif"'>Workshop format: serious attention will be given to hands-on practical exercises.<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif"'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif"'>After the Workshop:<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif"'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif"'>Several highly relevant BioSAXS-related sessions are scheduled for the beginning of the regular ACA meeting to immediately follow this workshop: TR.01 (Probing Biological Structure With HT SAS), 09.01 Dynamic & Flexible Structures in Biomolecules,<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif"'>09.03 Membrane Protein Scattering. Students of this workshop will be in an excellent position to take full advantage these cutting-edge presentations and are thus encouraged to attend and exchange ideas with the many SAS experts in attendance.<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif"'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif"'>For more information: <a href="http://www.amercrystalassn.org/wk.01"><span style='color:blue'>www.amercrystalassn.org/wk.01</span></a><o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif"'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif"'>*To Register: <a href="http://www.amercrystalassn.org/2013-registration"><span style='color:blue'>www.amercrystalassn.org/2013-registration</span></a><o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif"'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif"'>Note: students only attending the training Workshop do not need to pay the full ACA registration fee. <o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif"'>To register for just the workshop, fill out and return the ACA registration form (PDF file), paying the workshop fee only.<o:p></o:p></span></p><p class=MsoNormal style='text-align:justify'><span lang=FR style='color:#1F497D'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:10.0pt;font-family:"Calibri","sans-serif";color:gray'>Kushol Gupta, Ph.D.<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:10.0pt;font-family:"Calibri","sans-serif";color:gray'>Research Associate - Van Duyne Laboratory <o:p></o:p></span></p><p class=MsoNormal><span style='font-size:10.0pt;font-family:"Calibri","sans-serif";color:gray'>Perelman School of Medicine<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:10.0pt;font-family:"Calibri","sans-serif";color:gray'>University of Pennsylvania <o:p></o:p></span></p><p class=MsoNormal><span style='font-size:10.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><a href="BLOCKED::mailto:kgupta@stwing.upenn.edu" title="mailto:kgupta@stwing.upenn.edu"><span style='color:gray'>kgupta@mail.med.upenn.edu</span></a><o:p></o:p></span></p><p class=MsoNormal><span style='font-size:10.0pt;font-family:"Calibri","sans-serif";color:gray'>215-573-7260 / 267-259-0082<o:p></o:p></span></p><p class=MsoNormal style='text-align:justify'><span lang=FR style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><o:p> </o:p></span></p></div></body></html>