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</o:shapelayout></xml><![endif]--><div class="WordSection1"><p class="MsoNormal" style="font-family: Tahoma; font-size: 10pt; "><span style="font-size:11.0pt;font-family:"Calibri","sans-serif";mso-ascii-theme-font:minor-latin;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";mso-bidi-theme-font:minor-bidi;color:#1F497D;mso-themecolor:dark2">Hi, <o:p></o:p></span></p><p class="MsoNormal" style="font-family: Tahoma; font-size: 10pt; "><span style="font-size:11.0pt;font-family:"Calibri","sans-serif";mso-ascii-theme-font:minor-latin;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";mso-bidi-theme-font:minor-bidi;color:#1F497D;mso-themecolor:dark2">We bought a XL-A with FDS in 2007 or 2008, when I still was in Munich. I do not remember having seen that the machine stopped ones. I wonder if we were using a different version of the software (5.8 on that particular maching, with WinXP [most likely SP3]). The Xl-I I have here in MI is from 1997 (ran on Win2000 and now XP after the computer crashed) and does not stop either. </span><span class="Apple-style-span" style="color: rgb(31, 73, 125); font-family: Calibri, sans-serif; font-size: 15px; ">Both machines use Beckman/IBM computers. </span></p><p class="MsoNormal" style="font-family: Tahoma; font-size: 10pt; "><span style="font-size:11.0pt;font-family:"Calibri","sans-serif";mso-ascii-theme-font:minor-latin;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";mso-bidi-theme-font:minor-bidi;color:#1F497D;mso-themecolor:dark2"><o:p> </o:p></span></p><div style="font-family: Tahoma; font-size: 10pt; "><div style="border:none;border-top:solid #B5C4DF 1.0pt;padding:3.0pt 0in 0in 0in"><p class="MsoNormal"><b><span style="font-size:10.0pt;font-family:"Tahoma","sans-serif";mso-fareast-font-family:"Times New Roman";color:windowtext">From:</span></b><span style="font-size:10.0pt;font-family:"Tahoma","sans-serif";mso-fareast-font-family:"Times New Roman";color:windowtext"> rasmb-bounces@server1.bbri.org [mailto:rasmb-bounces@server1.bbri.org] <b>On Behalf Of </b>Ute <span class="SpellE">Curth</span><br><b>Sent:</b> Friday, March 11, 2011 6:05 AM<br><b>To:</b> rasmb@server1.bbri.org; ian.berke@yale.edu<br><b>Subject:</b> Re: [RASMB] CPU Board Malfunction on XL-I<o:p></o:p></span></p></div></div><p class="MsoNormal" style="font-family: Tahoma; font-size: 10pt; "><o:p> </o:p></p><p class="MsoNormal" style="font-family: Tahoma; font-size: 10pt; "><span lang="EN-GB" style="mso-ansi-language:EN-GB">Hi Ian,</span><o:p></o:p></p><p class="MsoNormal" style="font-family: Tahoma; font-size: 10pt; "><span lang="EN-GB" style="mso-ansi-language:EN-GB">we bought an XL-I equipped with an Aviv AU-FDS in 2008 and also suffer from severe problems. Either the centrifuge stops spinning or the computer stops scanning within a run. This happens after unpredictable times (20 min to 20 hours), at different rotor speeds (e.g. 22, 35 or 50 krpm), independent whether we measure absorbance only or absorbance and interference but not in every run. Our machine is still under warranty and Beckman has been trying for more than one year to solve this problem. A lot of components of the machine (all boards, the display, the radial drive....) were exchanged, but this did not solve the problem. After having ruled out that there were problems with the power supply in our institute, they admitted that there is a timing problem in the communication between centrifuge and computer and that similar problems exist in about 10 machines worldwide. Therefore, they modified the firmware and installed a new firmware pre-release (now the machine stopped scanning regularly in runs which were performed at 50000 rpm) and afterwards a new version of the GUI, which should solve this problem. In first tests with the new firmware/GUI combination the machine seems to work more reliable (it did not stop in several test runs at several speeds), but it turned out that the new firmware is not able to hand over the correct value for w^2t to the computer (a plot of w^2t against the time is not linear as expected, but looks like a saw tooth wave). They are trying to solve this problem for several weeks now and I still hope that our centrifuge will work properly soon. Just as a comment: the Aviv fluorescence detection system works without any problems.</span><o:p></o:p></p><p class="MsoNormal" style="font-family: Tahoma; font-size: 10pt; "><span lang="EN-GB" style="mso-ansi-language:EN-GB">Best wishes</span><o:p></o:p></p><p class="MsoNormal" style="font-family: Tahoma; font-size: 10pt; "><span lang="EN-GB" style="mso-ansi-language:EN-GB">Ute</span><o:p></o:p></p><pre style="font-family: Tahoma; font-size: 10pt; ">-- <o:p></o:p></pre><pre style="font-family: Tahoma; font-size: 10pt; ">PD Dr. rer. nat. Ute Curth<o:p></o:p></pre><pre style="font-family: Tahoma; font-size: 10pt; ">> Medizinische Hochschule Hannover<o:p></o:p></pre><pre style="font-family: Tahoma; font-size: 10pt; ">> Strukturanalyse<o:p></o:p></pre><pre style="font-family: Tahoma; font-size: 10pt; ">> OE 8830<o:p></o:p></pre><pre style="font-family: Tahoma; font-size: 10pt; ">> Carl-Neuberg-Str. 1<o:p></o:p></pre><pre style="font-family: Tahoma; font-size: 10pt; ">> 30625 Hannover<o:p></o:p></pre><pre style="font-family: Tahoma; font-size: 10pt; ">> Germany<o:p></o:p></pre><pre style="font-family: Tahoma; font-size: 10pt; ">> <o:p></o:p></pre><pre style="font-family: Tahoma; font-size: 10pt; ">> Tel.: +49-511-5329372<o:p></o:p></pre><pre style="font-family: Tahoma; font-size: 10pt; ">> Fax : +49-511-5322909<o:p></o:p></pre></div> </body>
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