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<DIV><SPAN class=939302709-17022009><FONT face="Bookman Old Style" size=2>Hello
all,</FONT></SPAN></DIV>
<DIV><SPAN class=939302709-17022009><FONT face="Bookman Old Style" size=2>If any
of you know an eager young UK national who would like to do a PhD between myself
and the Rutherford Appleton Laboratory, do let me know.</FONT></SPAN></DIV>
<DIV><SPAN class=939302709-17022009><FONT face="Bookman Old Style"
size=2>Details are below:</FONT></SPAN></DIV>
<DIV><SPAN class=939302709-17022009><FONT face="Bookman Old Style"
size=2></FONT></SPAN> </DIV>
<DIV><SPAN class=939302709-17022009><FONT face=Verdana size=2>PhD Studentship in
multi-scale solution structure analysis and modelling<BR><BR>One of the major
challenges of modern structural biology is the structural determination at high
resolution of biomolecules that are not amenable to crystallography or NMR. This
in includes biomolecules that are natively unstructured and large dynamic
assemblies. The challenge in tackling these systems lies in combining a range of
structural and biophysical techniques into an integrated approach capable of
utilising both low resolution and high resolution techniques in
combination.<BR><BR>This research will be carried out between the
Rutherford-Appleton Laboratory at Harwell (UK) and the National Centre for
Macromolecular Hydrodynamics at The University of Nottingham (UK). The student
will be trained in and utilise a wide range of structural and biophysical
techniques including small angle scattering, analytical ultacentrifugation, such
as protein crystallography, High-field NMR, small angle x-ray and neutron
scattering, and standard molecular biology techniques such as over-expression
and site-directed mutagenesis. In addition they will be closely involved in the
development of modelling approaches to combine the data from these techniques to
produce cohesive models of large scale and/or flexible structures.<BR><BR>The
position is jointly funded by the Science and Technology Funding Council (STFC)
and the Biotechnology and Biological Sciences Research Council (BBSRC), two of
the major funding agencies in the United Kingdom and is open to all UK
nationals. The position would suit biochemistry or chemistry graduates with an
interest in biological structure as well as graduates in physics or computer
science interested in expanding the application of their skills into the
practical sciences.<BR></FONT>
<BLOCKQUOTE><SPAN style="FONT-SIZE: 12px"><BR></SPAN></BLOCKQUOTE><SPAN
style="FONT-SIZE: 12px"><FONT face=Verdana>For further enquiries and details of
the project please contact Dr. Cameron Neylon (cameron.neylon@stfc.ac.uk) or Dr.
David Scott (dj.scott@nottingham.ac.uk). <BR></FONT></SPAN></SPAN></DIV>
<DIV> </DIV>
<DIV align=left><FONT face="Bookman Old Style" size=2></FONT> </DIV>
<DIV align=left><FONT face="Bookman Old Style"
size=2>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>></FONT></DIV>
<DIV align=left><FONT face="Bookman Old Style" size=2>Dr. David J.
Scott</FONT></DIV>
<DIV align=left><FONT face="Bookman Old Style" size=2>Associate Professor in
Physical Biochemistry</FONT></DIV>
<DIV align=left><FONT face="Bookman Old Style" size=2>National Centre for
Macromolecular Hydrodynamics</FONT></DIV>
<DIV align=left><FONT face="Bookman Old Style" size=2>School of
Biosciences</FONT></DIV>
<DIV align=left><FONT face="Bookman Old Style" size=2>Sutton Bonington
Campus</FONT></DIV>
<DIV align=left><FONT face="Bookman Old Style" size=2>University of
Nottingham</FONT></DIV>
<DIV align=left><FONT face="Bookman Old Style" size=2>Leicestershire. LE12
5RD.</FONT></DIV>
<DIV align=left><FONT face="Bookman Old Style" size=2>United
Kingdom.</FONT></DIV>
<DIV align=left><FONT face="Bookman Old Style" size=2>+44 115 951
6221</FONT></DIV>
<DIV align=left><FONT face="Bookman Old Style" size=2>+44 115 951
6142</FONT></DIV>
<DIV align=left><FONT face="Bookman Old Style" size=2><A
href="http://www.nottingham.ac.uk/ncmh">www.nottingham.ac.uk/ncmh</A></FONT></DIV>
<DIV align=left><FONT face="Bookman Old Style"
size=2>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>></FONT></DIV>
<DIV> </DIV></BODY><br/>
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