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Dear RASMBers:<br>
<br>
Two new biophysical characterization positions are open in our
department to support discovery of protein therapeutics. One is at the
Associate Research Scientist level (BS or MS degree required) and also
requires experience in protein purification. The other position is at
the Research Investigator level (PhD and preferably 2-3 years of
post-doctoral training required). Details are below. If interested,
please apply to the Bristol-Myers Squibb web site as
described below, and also send information direct to me. Please feel
welcome to call or email if you have any questions.<br>
<br>
Sincerely,<br>
Mike Doyle, PhD<br>
Group Leader, Protein Biochemistry<br>
(609) 252-3175<br>
<br>
<u>Job Description - Associate Research Scientist</u><br>
Express recombinant proteins in E. coli or yeast. Purify recombinant
proteins from E. coli, baculovirus infected insect cells, and other
sources. Ability to work independently and develop multi step
chromatography protein purification protocols from experience or from
researching the existing scientific literature. Biophysical
characterization of protein protein interactions using kinetic or
equilibrium methods. Characterize the protein structure, stability and
aggregation state of protein therapeutic agents and protein targets.
Closely collaborate with scientists within own department and with
external customers.<br>
<u>Position Requirements</u><br>
B.S. or M.S. in Biochemistry or related field. Two or more years of
post degree experience would be preferred. Experience with recombinant
DNA vectors and optimizing culture conditions to express milligram to
gram quantities of proteins in E. coli or yeast. Experience using
multi-step chromatography methods. Experience with analytical
ultracentrifugation, surface plasmon resonance, microcalorimetry, or
light scattering would be an advantage.<br>
<br>
<u>Job Description - Research Investigator</u><br>
Study protein-protein and protein-small molecule interactions to
support drug discovery. Use Analytical Ultracentrifugation, Surface
Plasmon Resonance, Calorimetry, Light Scattering and other biophysical
assays to select protein
therapeutic agents and characterize protein targets. Characterize of
protein structure, stability and
aggregation state. Conduct quantitative analysis of protein
interactions. Collaborate in multidisciplinary drug
discovery teams. Very strong communication skills are required, both
written and verbal.<br>
<u>Position Requirements</u><br>
PhD in Biochemistry or related field, and 2-3
years of postdoctoral
experience is preferred. The ideal candidate will have demonstrated
excellent scientific
leadership abilities as evidenced by publications and presentations at
scientific meetings. Biophysical characterization of
protein-protein
interactions using kinetic or equilibrium methods. Experience with
analytical
ultracentrifugation, surface plasmon resonance, or microcalorimetry
would be an advantage. Protein purification
experience would be an advantage. Effective verbal and written
communication skills.<br>
<br>
Applications must be made at
<a class="moz-txt-link-abbreviated" href="http://www.bms.com">www.bms.com</a>
(click on "Job Search" in the "Quick Links" section in middle of web
page, and register). To apply, register as a guest, locate the
position by doing a "detailed search" with the requisition
number 19902 (Associate Scientist, BS/MS) or 19867 (Research
Investigator, PhD w/post-doc) . (Please also send your CV to <a
class="moz-txt-link-abbreviated" href="mailto:michael.doyle@bms.com">michael.doyle@bms.com</a>).<br>
<br>
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