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--></style><title>SOMO: a new program for constructing hydrodynamic
bead mod</title></head><body>
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<div><font color="#000000">Hi Everyone,<br>
<br>
We'd like to draw your attention to the release of a new program for
constructing hydrodynamic bead models. SOMO generates models from
atomic coordinates (of proteins and carbohydrates) and retains the
local characteristics of the macromolecule (i.e. beads correspond with
amino acids etc). It also "intelligently" hydrates the
model. Hydrodynamic parameters for SOMO models can then be computed
either with José García de la Torre's group's program (HYDRO) or
with Mattia Rocco's group's program (SUPC).<br>
<br>
The program is described in the recent volume of Structure:<br>
<br>
http://www.structure.org/<br>
<br>
On a note of shameless self-publicity we'd like to advise you that our
paper features on the cover of the journal. We mention this
because we feel it raises the profile of hydrodynamics in general and
bead modelling in particular and that it may be of use to some of you
in persuading funding agencies to support this aspect of your
work.<br>
<br>
Finally, we invite you to download the program from</font><br>
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<div><font
color="#000000"
>http://malvinas.molgen.gla.ac.uk/~mrc/Public/somo_old/somo_home.htm</font
></div>
<div><font size="-2" color="#000000"><br>
</font><font color="#000000">and to try it out.<br>
<br>
We're very interested to hear from users and we're happy to advise on
the use of SOMO in any way we can. In addition we'd like to hear
from you any comments you may have about the future of hydrodynamic
modelling so that we can try to address them as we continue to develop
SOMO.<br>
<br>
With best wishes-<br>
<br>
Mattia Rocco and Olwyn Byron</font></div>
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<br>
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