[RASMB] [EXTERNAL] Serum and EH&S

[John J. Correia]

John, my lab has been doing human serum proteins and human serum runs without concerns (see attached for relevant studies). When you buy human serum it's been tested for infectious material. The normal precautions of wearing gloves, a face mask, and then cleaning cell components are encouraged. Interpretation of the data is a bit harder since you must include ks and BM1 cross term values and thus know something about the serum composition and its interaction with your system of interest. This is part of the ongoing part of our work in this area.

From: RASMB [mailto:rasmb-bounces at list.rasmb.org] On Behalf Of John Sumida
Sent: Wednesday, September 26, 2018 5:00 PM
To: RASMB <rasmb at list.rasmb.org>
Subject: [EXTERNAL] [RASMB] Serum and EH&S

Dear RASMB,

I apologize that this is not a scientific question, but this is, perhaps, a question that has come up for some on the list and I would be curious to hear how it was handled.

We periodically field requests to spin human serum solutions, which invariably is a health & safety problem due to the potential for a cell leak and the subsequent aerosolization of a potentially hazardous material into the lab environment.

As an academic lab, our resources and institutional motivation in engineering a space specific for this application are limited.  Thus, one suggestion was to use third party testing of samples being submitted for analysis.  However this is costly and most users have abandoned their efforts to perform these measurements as a result.

I would be curious to know if third party testing of potentially infectious materials such as human serum is commonly used within an EH&S setting, or if it is possible to place a HEPA filter in the vacuum exhaust if the instrument uses a TMP?

Thank you in advance for any information you may be able to offer.

Best regards
John Sumida
University of Washington.
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