[RASMB] Request for proposals on characterizing sub-visible particulates

[Tom Laue]

*Request for Proposal*

*Methods for characterizing sub-visible particulates*

The detection and characterization of sub-visible particulates in 
solution is of increasing concern to the pharmaceutical industry. The 
Biomolecular Interaction Technologies Center (BITC, www.bitc.unh.edu 
<http://www.bitc.unh.edu/>), a National Science Foundation 
Industry/University Cooperative Research Center, is soliciting proposals 
for novel or improved methods for characterizing sub-visible (0.1 – 5 
μm) particulates.

This RFP focuses on the development or characterization of new or 
improved instrumentation or methods for detecting small quantities of 
sub-visible particulates and for characterizing the size of the 
particulates.

Parameters that are of particular interest include:

1.What size ranges are accessible by the method?

2.What is the sensitivity limit?

3.How does the sensitivity of the method vary over the size range?

4.How well are different sized particulates discriminated?

a)Is a histogram of the size distribution provided?

5.What are the solvent requirements/limitations?

Researchers at academic institutions are eligible to apply. The research 
must be conducted within the U.S. Awards typically range from $15,000 to 
$50,000 per year; project duration is typically two years. Researchers 
are encouraged to cite BITC support in proposals for funding from other 
sources, to use BITC funds to leverage grants and other funding 
opportunities, to support a portion of an instrument development 
project, or to support a graduate student or postdoctoral appointment. 
Institution overhead fees are held at 10% at the request of the NSF 
IUCRC program.

Submit a proposal via email as either an RTF or Word document, or as a 
PDF (deadline below). Proposals must be received by June 1^st 2011 and 
include a description of the project, estimated cost, duration, and 
credentials of the principal investigator. Email to: Dr. Thomas M. Laue, 
bitc.unh at unh.edu.



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Department of Biochemistry and Molecular Biology
University of New Hampshire
Durham, NH 03824-3544
Phone: 603-862-2459
FAX:   603-862-0031
E-mail: Tom.Laue at unh.edu
www.bitc.unh.edu
www.camis.unh.edu