[RASMB] V-bar calculation for mAb

[sumit goswami]

Hello all,
             I was trying to calculate v-bar of a mAb using SEDNTERP. I have
the sequence of heavy chain (HC) and light chain (LC) seperately as
expected. It seems to be little complicated. Because there are HC-HC and
LC-LC disulfide linkages too.The question is how do I deal with that? Should
I calculate the v-bar of Fab and Fc seperately and then calculate an weight
avergae of them?

With regards,
Sumit
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