[RASMB] everything sediments... some things float

[Holger Strauss]

Hello everybody,

recently, a sample finally found its way to me that has floating AND 
sedimenting (macromolecular) components. Both are detected and it is 
important to characterize both, at least their partial concentrations. 
So.... did I mention already that both fractions are polydisperse?

As far as I'm aware, no Lamm-equation based algorithm will calculate a 
distribution going from negative to positive. Please do correct me if 
I'm wrong!
I've performed synthetic boundary runs, so at least I have data with 
upper and lower plateaus. Any suggestions on how to treat these data in 
a model-independent way, i.e. where to put the (permeable) meniscus? 
(Walter, my hopes are somewhat resting on Sedanal...?)
Have the ancient masters encountered anything like that before? How did 
they deal with it?

Best wishes to all of you,
Holger

-- 
Nanolytics
Gesellschaft fuer Kolloidanalytik mbH
Dr. Holger Strauss

Am Muehlenberg 11
D-14476 Potsdam
Tel: +49 331 5818360
Fax: +49 331 5818361
e-mail:	strauss at nanolytics.de
Internet:  www.nanolytics.de
_______________________________________________
Diese E-Mail kann vertrauliche und/oder rechtlich geschützte Informationen enthalten. Wenn Sie nicht der richtige Adressat sind oder diese E-Mail irrtümlich erhalten haben, informieren Sie bitte sofort den Absender und vernichten Sie diese Mail. Das unerlaubte Kopieren sowie die unbefugte Weitergabe dieser Mail ist nicht gestattet.

This e-mail may contain confidential and/or privileged information. If you are not the intended recipient (or have received this e-mail in error) please notify the sender immediately and destroy this e-mail. Any unauthorized copying, disclosure or distribution of the material in this e-mail is strictly forbidden.