[RASMB] detecting virus particles with AUC

Veysel Kayser vkayser at MIT.EDU
Thu Sep 25 10:34:21 PDT 2008


Dear AUC experts,

Is it possible to detect virus particles (aggregated and disassembled  
viruses as well monomers) in AUC? If so, what would be the  
recommended concentration and speed for spinning them? In addition,  
what is the sensitivity of AUC, e.g. can one detect monomer, dimer  
and smaller particles at the same time? The virus has a bullet shape  
with 100nm X 200nm size. Any input would be appreciated.

Veysel



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