[RASMB] A Complicated Equilibrium Problem

[Eric Salgado]

Hello,
   I have a system that contains four different molecular weight species 
of my protein ( monomer, dimer, trimer, hexamer), all mediated by Nickel 
coordination. I can see this through previous SV experiments, as well as 
the species analysis model in SEDPHAT. I cannot, however, determine any 
dissociation constants using any of the pre-existing models in that 
program. I'm thinking that there might be competing monomer-dimer and 
monomer-trimer-hexamer equilibriums, or some combination thereof.
   With all of this in mind, I was wondering if there was a program with 
a model such as this that I might employ, or if it would be possible to 
add my own model to such programs as Heteroanaylsis, Sedphat, etc.
    Thank you for your time and advice in advance,
      
       Eric Salgado
       Univ. Cal. San Diego
       Dept. Chemistry and Biochemistry