[RASMB] nucleic acid vbar

[John Correia]

Bloomfield, Crothers & Tinoco show the salt dependence of vbar for Cs and NaDNA (taken from Eisenberg (1976), so .55 is a traditional starting point, not a fact.

>>> On 8/26/2007 at 2:56 PM, in message <200708261956.l7QJuWtc008982 at biochem.uthscsa.edu>, Borries Demeler <demeler at biochem.uthscsa.edu> wrote:
There seems to be a consensus to use a vbar of .55 ccm/g for DNA and RNA. Does
anyone know if there is a function that predicts variations in vbar with temperature
like there is for peptides? Or is .55 the best value to use - are there any
references on this?

Thanks, -borries
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