[RASMB] NIH Workshop on Hydrodynamic and Thermodynamic Analysis of Macromolecules with SEDFIT and SEDPHAT
Peter Schuck
pschuck at helix.nih.gov
Thu Aug 23 08:51:56 PDT 2007
Dear Colleagues,
this is to announce the upcoming
Workshop on Hydrodynamic and Thermodynamic Analysis of Macromolecules with
SEDFIT and SEDPHAT
which will take place from September 24-28, 2007 at the NIH campus in
Bethesda, Maryland (USA).
This workshop will review strategies for hydrodynamic and thermodynamic
analysis of sedimentation equilibrium and sedimentation velocity analytical
ultracentrifugation (AUC), dynamic light scattering (DLS), and isothermal
titration calorimetry (ITC) for the characterization of biological
macromolecules in solution.
The workshop will start on Monday morning and end on Friday at noon. On
the first day, we will provide an introduction into the experimental
aspects of AUC, DLS and ITC. This part will take place in the
laboratory. We will review the basic operation of the instruments, choice
of buffers, and detection systems, and experimental design dependent on the
system under study. For AUC, assembling the AUC cells and operating the
XLA/I will be discussed in detail. The following days, will cover many
advanced topics of theory, data analysis and experimental setup. These
lectures are accompanied by practical computer exercises with the software.
We will introduce at the workshop also several new features, including our
new Bayesian analysis approach for enhanced resolution and sensitivity in
c(s), a new Sedfit version with significantly enhanced user
interface, faster Lamm equation solutions and multi-thread support, and
many other new features.
A detailed description and how to register can be found here:
http://www.analyticalultracentrifugation.com/workshop.htm
Sincerely,
Peter Schuck
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