[RASMB] fitting sigma and K values using Nonlin

[ljs at mail.csb.yale.edu]

Dear all,

Thank you so much for your response and advice re:  temperature dependence of 
the Vbar value for RNA.  

I have been spending some time getting acquainted with Nonlin recently, and 
would like to know the following:

For a self-associating monomer-dimer system in which the mw of the monomer is 
known, should I fix the sigma value to obtain lnK2 during the fitting?  Or, 
should I float both sigma and lnK2?

Also:  Are there any plans for an online tutorial for Nonlin?

Thanks so much for your help!

Regards,

Julie Su
ljs at mail.csb.yale.edu