[RASMB] book and review

John Philo jphilo at mailway.com
Thu May 16 17:12:00 PDT 2002


The AU crowd may be interested in a book reviewed in this week's Nature (9
May, p. 121):

Meselson, Stahl, and the Replication of DNA: A History of "The Most
Beautiful Experiment in Biology" by Frederic Lawrence Holmes (Yale
University Press, 2001)

This covers the experiments proving the semi-conservative replication of
DNA, done of course in the model E using N15 labeled DNA and cesium chloride
density gradient equilibrium (actually done in the Vinograd lab).

There is a picture in Nature of Matthew Meselson in front of the Model E.

It's nice to see this classic work getting some attention---I don't think
today's students have any idea how these important concepts were proven.

Greetings and best regards to all,

John Philo




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